Objective To investigate a possible association between fever admissions and 4 component Meningococcal B (4CMenB). Design 4CMenB is given at 8 and 16 weeks in the first year of life. Self-controlled ...

We encounter, occasionally, parents who are incapable of making medical decisions on behalf of their incompetent or incapacitated children. When the incapable parent is themselves a child; measures ...

Background Gender identity services for children and young people are currently being reorganised in England and Wales. Provision is required to negotiate clinical uncertainty and a public debate that ...

Background Over the last few years, there has been increasing attention to the involvement of the central nervous system in Duchenne muscular dystrophy (DMD). The aim of this study was to assess the ...

Background The gold standard of paediatric obstructive sleep apnoea syndrome (OSAS) diagnosis is overnight polysomnography (PSG). Validated screening methods for paediatric OSAS are limited.

The relief of pain and anxiety associated with painful or invasive procedures is a top priority in paediatrics. A ‘Sounding Board’ in the New England Journal of Medicine 30 years ago stated that ‘The ...

Nirsevimab, a long-acting monoclonal antibody, was introduced last season (2023–2024) in some countries with the aim of reducing the burden of disease caused by respiratory syncytial virus (RSV) in ...

Objective To evaluate the efficacy differentials among corticosteroid regimens by type, dosage and duration, we conducted a systematic review and network meta-analysis of randomised controlled trials ...

Background/aim Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are rare imprinting disorders caused by the aberrant expression of 15q11.2-q13 imprinted genes. Due to their rarity, data on ...

Objective To validate a short parent-reported outcome (PRO) questionnaire in young boys with conditions affecting sex development (PRO-CSD). Design Consecutive sample cross-sectional study. Setting A ...

Objectives To evaluate the appropriateness of the American Academy of Pediatrics’ (AAP) recommendation to no longer collect a urine culture (UC) in febrile infants ≥21 days old with negative ...

A 3-week-old infant is diagnosed with tuberous sclerosis complex (TSC) after cardiac rhabdomyomas are detected on prenatal ultrasound and a pathogenic variant in TSC2 is confirmed postnatally through ...