SportsLine expert Micah Roberts has revealed his Duke Blue Devils vs. Houston Cougars picks for the Final Four of the 2025 NCAA Tournament on Saturday

The Duke Blue Devils face the Houston Cougars in the Final Four of the men’s NCAA Tournament at the Alamodome in San Antonio, Texas, on Saturday, April 5, 2025.

Ahead of Saturday's Final Four showdown between UH and Duke, CBS' announcing crew offers its thoughts on the matchup and keys to victory.

NCAA Tournament has reached the Final Four. For the second time in the history of March Madness, all four No. 1 seeds advanced to the Final Four and now we'll see Auburn, Houston, Duke and Florida battle it out for the title on Saturday.

Madness wager between a pro gambler and an artificial-intelligence site will be decided by the winner of the Duke-Houston game in the Final Four.

What are Final Four odds now? What to know about Houston Cougars vs Duke Blue Devils point spread, moneyline, over/under for March Madness betting.

One method bettors love when wagering on sports is the same game parlay. This works by combining multiple bets from the same contest into one bet slip to boost the overall odds and create a more lucrative payout. However, this bet is only successful if each leg is correct, so be careful.

Check out our expert player prop bets for Auburn vs. Florida and Duke vs. Houston in the Final Four Saturday night.

NCAA Tournament Final Four matchup between the Duke Blue Devils and Houston Cougars with predictions, odds, picks, spread, betting lines and more.