While the U.S. insists it is not involved in strikes on Iran, American officials have confirmed military forces have been helping to intercept Iranian missiles fired at Israel.

Israeli Prime Minister Benjamin Netanyahu is on the mission of his lifetime. For years, the veteran leader has made the destruction of Iran’s nuclear program his top priority.

It follows daytime attacks from both sides, with Israeli strikes in Tehran continuing and Iran firing more missiles towards Israel.

Oil prices climbed on Monday, extending Friday's rally, as renewed strikes by Israel and Iran over the weekend increased concerns that the battle could widen across the region and significantly disrupt oil exports from the Middle East.

Several buildings in Israel’s Weizmann Institute of Science, one of the country’s top research centers, were damaged in an Iranian strike but there were no casualties, its management told its community members.

New targets appear to indicate an expansion of Israel’s war aims beyond the Iranian nuclear facilities that consumed the first days of the conflict.

Iranian Foreign Minister Abbas Araghchi said Sunday that if the Israeli strikes on Iran stop, then “our responses will also stop.”

Israel and Iran have opened a new chapter in their long history of conflict when Israel launched a major attack with strikes early Friday on Tehran.