In the latest 2025 NFL mock draft for ESPN, the San Francisco 49ers have a clear direction in which they want to head. ESPN’s Matt Miller shared his latest two-round mock draft following the Senior Bowl and Shrine Bowl all-star events. It has the 49ers looking to the trenches for help.

In this two-round 2025 NFL mock draft from ESPN, the Chicago Bears enhance their offense with their first two selections, including a bruising RB in Round 2.

NFL mock drafts have the Seattle Seahawks addressing the offensive line early. That's the baseline expectation, considering the Seahawks have massive needs across the interior of their O-line, and arguably at right guard as well.